Virginia, 1803. After the United States of America acquires the inmense Louisiana territory from France, a great expedition, led by William Lewis and Meriwether Clark, is sent to survey the new lands and go where no white man has gone before.
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Fred MacMurray
Cpt. Meriwether Lewis
Charlton Heston
Lt. William Clark
Donna Reed
Sacajawea
Barbara Hale
Julia Hancock
William Demarest
Sgt. Gass
Alan Reed
Charbonneau
Eduardo Noriega
Chief Cameahwait
Larry Pennell
Wild Eagle
Herbert Heyes
President Thomas Jefferson
Lester Matthews
Mr. Hancock
Argentina Brunetti
Shoshone Woman (uncredited)
Julia Montoya
Crow Woman (uncredited)
Ralph Moody
Chief Le Borgne (uncredited)
William Phipps
Night Camp Sentry (uncredited)
Walter Reed
Helmsman Cruzatte (uncredited)
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